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Saccharomyces cerevisiae as a Model System To Define the Chromosomal Instability Phenotype

Translocations, deletions, and chromosome fusions are frequent events seen in cancers with genome instability. Here we analyzed 358 genome rearrangements generated in Saccharomyces cerevisiae selected by the loss of the nonessential terminal segment of chromosome V. The rearrangements appeared to be...

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Detalhes bibliográficos
Main Authors: Putnam, Christopher D., Pennaneach, Vincent, Kolodner, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190249/
https://ncbi.nlm.nih.gov/pubmed/16055731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7226-7238.2005
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