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Identification and Quantification of Oxidation Products in Full-Length Biotherapeutic Antibodies by NMR Spectroscopy
[Image: see text] Therapeutic proteins are an indispensable class of drugs and often therapeutics of last resort. They are sensitive to oxidation, which is of critical concern, because it can affect drug safety and efficacy. Protein oxidation, with methionine and tryptophan as the most susceptible m...
Guardat en:
| Publicat a: | Anal Chem |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical
Society
2020
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7467420/ https://ncbi.nlm.nih.gov/pubmed/32530275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c00965 |
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