Wordt geladen...
Detecting aspartate isomerization and backbone cleavage after aspartate in intact proteins by NMR spectroscopy
The monitoring of non-enzymatic post-translational modifications (PTMs) in therapeutic proteins is important to ensure drug safety and efficacy. Together with methionine and asparagine, aspartic acid (Asp) is very sensitive to spontaneous alterations. In particular, Asp residues can undergo isomeriz...
Bewaard in:
| Gepubliceerd in: | J Biomol NMR |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer Netherlands
2021
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7897204/ https://ncbi.nlm.nih.gov/pubmed/33475951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-020-00356-4 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|