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A comparison of humans and baboons suggests germline mutation rates do not track cell divisions

In humans, most germline mutations are inherited from the father. This observation has been widely interpreted as reflecting the replication errors that accrue during spermatogenesis. If so, the male bias in mutation should be substantially lower in a closely related species with similar rates of sp...

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Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Wu, Felix L., Strand, Alva I., Cox, Laura A., Ober, Carole, Wall, Jeffrey D., Moorjani, Priya, Przeworski, Molly
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467331/
https://ncbi.nlm.nih.gov/pubmed/32804933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000838
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