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A comparison of humans and baboons suggests germline mutation rates do not track cell divisions

In humans, most germline mutations are inherited from the father. This observation has been widely interpreted as reflecting the replication errors that accrue during spermatogenesis. If so, the male bias in mutation should be substantially lower in a closely related species with similar rates of sp...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Wu, Felix L., Strand, Alva I., Cox, Laura A., Ober, Carole, Wall, Jeffrey D., Moorjani, Priya, Przeworski, Molly
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467331/
https://ncbi.nlm.nih.gov/pubmed/32804933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000838
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