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A comparison of humans and baboons suggests germline mutation rates do not track cell divisions

In humans, most germline mutations are inherited from the father. This observation has been widely interpreted as reflecting the replication errors that accrue during spermatogenesis. If so, the male bias in mutation should be substantially lower in a closely related species with similar rates of sp...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Wu, Felix L., Strand, Alva I., Cox, Laura A., Ober, Carole, Wall, Jeffrey D., Moorjani, Priya, Przeworski, Molly
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467331/
https://ncbi.nlm.nih.gov/pubmed/32804933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000838
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