Učitavanje...

Overlooked roles of DNA damage and maternal age in generating human germline mutations

The textbook view that most germline mutations in mammals arise from replication errors is indirectly supported by the fact that there are both more mutations and more cell divisions in the male than in the female germline. When analyzing large de novo mutation datasets in humans, we find multiple l...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Gao, Ziyue, Moorjani, Priya, Sasani, Thomas A., Pedersen, Brent S., Quinlan, Aaron R., Jorde, Lynn B., Amster, Guy, Przeworski, Molly
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511033/
https://ncbi.nlm.nih.gov/pubmed/31019089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901259116
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!