Histone Demethylase KDM5B as a Therapeutic Target for Cancer Therapy

Lysine-specific demethylase 5B (KDM5B/PLU1/JARID1B) is found to be overexpressed in numerous malignancies, including breast, lung, skin, liver, and prostate cancer. Identification of molecules targeting the KDM5B enzyme could be a potential lead in cancer research. Although many KDM5B inhibitors wit...

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Dades bibliogràfiques
Publicat a:Cancers (Basel)
Autors principals: Jose, Anmi, Shenoy, Gautham G., Sunil Rodrigues, Gabriel, Kumar, Naveena A. N., Munisamy, Murali, Thomas, Levin, Kolesar, Jill, Rai, Ganesha, Rao, Praveen P. N., Rao, Mahadev
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465382/
https://ncbi.nlm.nih.gov/pubmed/32751840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082121
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