Histone Demethylase KDM5B as a Therapeutic Target for Cancer Therapy

Lysine-specific demethylase 5B (KDM5B/PLU1/JARID1B) is found to be overexpressed in numerous malignancies, including breast, lung, skin, liver, and prostate cancer. Identification of molecules targeting the KDM5B enzyme could be a potential lead in cancer research. Although many KDM5B inhibitors wit...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Jose, Anmi, Shenoy, Gautham G., Sunil Rodrigues, Gabriel, Kumar, Naveena A. N., Munisamy, Murali, Thomas, Levin, Kolesar, Jill, Rai, Ganesha, Rao, Praveen P. N., Rao, Mahadev
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465382/
https://ncbi.nlm.nih.gov/pubmed/32751840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082121
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