The Clinical Significance of RAS, PIK3CA, and PTEN Mutations in Non-Small Cell Lung Cancer Using Cell-Free DNA

Mutations in the EGFR gene downstream signaling pathways may cause receptor-independent pathway activation, making tumors unresponsive to EGFR inhibitors. However, the clinical significance of RAS, PIK3CA or PTEN mutations in NSCLC is unclear. In this study, patients who were initially diagnosed wit...

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Bibliografiske detaljer
Udgivet i:J Clin Med
Main Authors: Chang, Won Jin, Sung, Jae Sook, Lee, Sung Yong, Kang, Eun Joo, Kwon, Nak-Jung, Kim, Hae Mi, Shin, Sang Won, Choi, Jung Yoon, Choi, Yoon Ji, Kim, Ju Won, Park, Kyong Hwa, Kim, Yeul Hong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7465200/
https://ncbi.nlm.nih.gov/pubmed/32823871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9082642
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