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Detection of K-ras Mutation in Serum DNA of Colon Cancer Patients

BACKGROUND: Activating mutations of the K-ras gene, a known oncogene, are found in a large proportion of human tumors. In particular, up to 80∼90% of colon cancers contain K-ras mutations, which are associated with treatment failure and poor prognosis. In current clinical diagnostic procedures, howe...

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Bibliografiske detaljer
Main Authors: Kim, Jin, Park, Sung Soo, Joo, Hyun-Jung, Sung, Jae Sook, Park, Kyong Hwa, Kim, Yeul Hong
Format: Artigo
Sprog:Inglês
Udgivet: International Society of Gastrointestinal Oncology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056295/
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