Dose KRAS Mutation Status Affect on the Effect of VEGF Therapy in Metastatic Colon Cancer Patients?

PURPOSE: Mutations affecting the KRAS gene are an established negative predictor for anti-epidermal growth factor receptor (anti-EGFR) therapies in metastatic colorectal cancer (CRC). However, the role of KRAS mutation as a biomarker for anti-vascular endothelial growth factor (VEGF) remains controv...

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Hlavní autoři: Kim, Seung Tae, Park, Kyong Hwa, Shin, Sang Won, Kim, Yeul Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Cancer Association 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918527/
https://ncbi.nlm.nih.gov/pubmed/24520223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2014.46.1.48
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