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Activation of p53-Dependent Growth Suppression in Human Cells by Mutations in PTEN or PIK3CA
In an effort to identify genes whose expression is regulated by activated phosphatidylinositol 3-kinase (PI3K) signaling, we performed microarray analysis and subsequent quantitative reverse transcription-PCR on an isogenic set of PTEN gene-targeted human cancer cells. Numerous p53 effectors were up...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800819/ https://ncbi.nlm.nih.gov/pubmed/17060456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00537-06 |
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