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Intraneuronal Tau Misfolding Induced by Extracellular Amyloid-β Oligomers
Abnormal folding and aggregation of the microtubule-associated protein, Tau, is a hallmark of several neurodegenerative disorders, including Alzheimer’s disease (AD). Although normal Tau is an intrinsically disordered protein, it does exhibit tertiary structure whereby the N- and C-termini are often...
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| Publicado no: | J Alzheimers Dis |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7464573/ https://ncbi.nlm.nih.gov/pubmed/31524157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190226 |
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