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TLR3-Dependent Activation of TLR2 Endogenous Ligands via the MyD88 Signaling Pathway Augments the Innate Immune Response

The role of the adaptor molecule MyD88 is thought to be independent of Toll-like receptor 3 (TLR3) signaling. In this report, we demonstrate a previously unknown role of MyD88 in TLR3 signaling in inducing endogenous ligands of TLR2 to elicit innate immune responses. Of the various TLR ligands exami...

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Dades bibliogràfiques
Publicat a:Cells
Autors principals: Teixeira, Hellen S., Zhao, Jiawei, Kazmierski, Ethan, Kinane, Denis F., Benakanakere, Manjunatha R.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464415/
https://ncbi.nlm.nih.gov/pubmed/32824595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081910
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