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TLR3-Dependent Activation of TLR2 Endogenous Ligands via the MyD88 Signaling Pathway Augments the Innate Immune Response

The role of the adaptor molecule MyD88 is thought to be independent of Toll-like receptor 3 (TLR3) signaling. In this report, we demonstrate a previously unknown role of MyD88 in TLR3 signaling in inducing endogenous ligands of TLR2 to elicit innate immune responses. Of the various TLR ligands exami...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Teixeira, Hellen S., Zhao, Jiawei, Kazmierski, Ethan, Kinane, Denis F., Benakanakere, Manjunatha R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464415/
https://ncbi.nlm.nih.gov/pubmed/32824595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081910
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