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Chondrocyte Innate Immune MyD88-dependent Signaling Drives Pro-Catabolic Effects of the Endogenous TLR2/TLR4 Ligands LMW-HA and HMGB1
OBJECTIVE: TLR2/TLR4-mediated innate immunity serves in frontline antimicrobial host defense, but also modulates tissue remodeling and repair responses to endogenous ligands released in low-grade inflammatory diseases. Here, we assessed if the endogenous TLR2/TLR4 ligands low molecular weight hyalur...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902571/ https://ncbi.nlm.nih.gov/pubmed/20506365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27475 |
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