Transport Oligonucleotides—A Novel System for Intracellular Delivery of Antisense Therapeutics

Biological activity of antisense oligonucleotides (asON), especially those with a neutral backbone, is often attenuated by poor cellular accumulation. In the present proof-of-concept study, we propose a novel delivery system for asONs which implies the delivery of modified antisense oligonucleotides...

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Publicat a:Molecules
Autors principals: Markov, Oleg V., Filatov, Anton V., Kupryushkin, Maxim S., Chernikov, Ivan V., Patutina, Olga A., Strunov, Anton A., Chernolovskaya, Elena L., Vlassov, Valentin V., Pyshnyi, Dmitrii V., Zenkova, Marina A.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464317/
https://ncbi.nlm.nih.gov/pubmed/32796768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25163663
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