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Endogenous Ribonucleases: Therapeutic Targeting of the Transcriptome Through Oligonucleotide-Triggered RNA Inactivation

The selective regulation of gene expression at the RNA level represents a rapidly evolving field offering substantial clinical potential. This review examines the molecular mechanisms of intracellular enzymatic systems that utilize single-stranded nucleic acids to downregulate specific RNA targets....

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Principais autores: Daria A. Chiglintseva, Olga A. Patutina, Marina A. Zenkova
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2025-07-01
Serija:Biomolecules
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Online dostop:https://www.mdpi.com/2218-273X/15/7/965
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