Transport Oligonucleotides—A Novel System for Intracellular Delivery of Antisense Therapeutics

Biological activity of antisense oligonucleotides (asON), especially those with a neutral backbone, is often attenuated by poor cellular accumulation. In the present proof-of-concept study, we propose a novel delivery system for asONs which implies the delivery of modified antisense oligonucleotides...

Full description

Saved in:
Bibliographic Details
Published in:Molecules
Main Authors: Markov, Oleg V., Filatov, Anton V., Kupryushkin, Maxim S., Chernikov, Ivan V., Patutina, Olga A., Strunov, Anton A., Chernolovskaya, Elena L., Vlassov, Valentin V., Pyshnyi, Dmitrii V., Zenkova, Marina A.
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464317/
https://ncbi.nlm.nih.gov/pubmed/32796768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25163663
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items