Knockdown of Leptin Receptor Affects Macrophage Phenotype in the Tumor Microenvironment Inhibiting Breast Cancer Growth and Progression

Aberrant leptin (Ob) signaling, a hallmark of obesity, has been recognized to influence breast cancer (BC) biology within the tumor microenvironment (TME). Here, we evaluated the impact of leptin receptor (ObR) knockdown in affecting BC phenotype and in mediating the interaction between tumor cells...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Gelsomino, Luca, Naimo, Giuseppina Daniela, Malivindi, Rocco, Augimeri, Giuseppina, Panza, Salvatore, Giordano, Cinzia, Barone, Ines, Bonofiglio, Daniela, Mauro, Loredana, Catalano, Stefania, Andò, Sebastiano
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464041/
https://ncbi.nlm.nih.gov/pubmed/32727138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082078
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