The Multifaceted Mechanism of Leptin Signaling within Tumor Microenvironment in Driving Breast Cancer Growth and Progression

Adipokines represent likely candidates to mediate the increased breast cancer risk and the enhanced progression associated with obesity. Other contributors to obesity-related cancer progression are insulin/IGF-1 pathways and hormones. Among these, the adipokine leptin is the most intensively studied...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Andò, Sebastiano, Barone, Ines, Giordano, Cinzia, Bonofiglio, Daniela, Catalano, Stefania
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245002/
https://ncbi.nlm.nih.gov/pubmed/25505738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00340
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