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Knockdown of Leptin Receptor Affects Macrophage Phenotype in the Tumor Microenvironment Inhibiting Breast Cancer Growth and Progression

Aberrant leptin (Ob) signaling, a hallmark of obesity, has been recognized to influence breast cancer (BC) biology within the tumor microenvironment (TME). Here, we evaluated the impact of leptin receptor (ObR) knockdown in affecting BC phenotype and in mediating the interaction between tumor cells...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Gelsomino, Luca, Naimo, Giuseppina Daniela, Malivindi, Rocco, Augimeri, Giuseppina, Panza, Salvatore, Giordano, Cinzia, Barone, Ines, Bonofiglio, Daniela, Mauro, Loredana, Catalano, Stefania, Andò, Sebastiano
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464041/
https://ncbi.nlm.nih.gov/pubmed/32727138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082078
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