Knockdown of Leptin Receptor Affects Macrophage Phenotype in the Tumor Microenvironment Inhibiting Breast Cancer Growth and Progression

Aberrant leptin (Ob) signaling, a hallmark of obesity, has been recognized to influence breast cancer (BC) biology within the tumor microenvironment (TME). Here, we evaluated the impact of leptin receptor (ObR) knockdown in affecting BC phenotype and in mediating the interaction between tumor cells...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Gelsomino, Luca, Naimo, Giuseppina Daniela, Malivindi, Rocco, Augimeri, Giuseppina, Panza, Salvatore, Giordano, Cinzia, Barone, Ines, Bonofiglio, Daniela, Mauro, Loredana, Catalano, Stefania, Andò, Sebastiano
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464041/
https://ncbi.nlm.nih.gov/pubmed/32727138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082078
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