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Engineering Solutions for Mitigation of Chimeric Antigen Receptor T-Cell Dysfunction

The clinical successes of chimeric antigen receptor (CAR)-T-cell therapy targeting cell surface antigens in B cell leukaemias and lymphomas has demonstrated the proof of concept that appropriately engineered T-cells have the capacity to destroy advanced cancer with long term remissions ensuing. Neve...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Gavriil, Artemis, Barisa, Marta, Halliwell, Emma, Anderson, John
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463974/
https://ncbi.nlm.nih.gov/pubmed/32824734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082326
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