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Engineering chimeric antigen receptor-T cells for cancer treatment

Intratumor heterogeneity of tumor clones and an immunosuppressive microenvironment in cancer ecosystems contribute to inherent difficulties for tumor treatment. Recently, chimeric antigen receptor (CAR) T-cell therapy has been successfully applied in the treatment of B-cell malignancies, underscorin...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Ye, Baixin, Stary, Creed M., Li, Xuejun, Gao, Qingping, Kang, Chunsheng, Xiong, Xiaoxing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815249/
https://ncbi.nlm.nih.gov/pubmed/29448937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0814-0
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