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Engineering chimeric antigen receptor-T cells for cancer treatment

Intratumor heterogeneity of tumor clones and an immunosuppressive microenvironment in cancer ecosystems contribute to inherent difficulties for tumor treatment. Recently, chimeric antigen receptor (CAR) T-cell therapy has been successfully applied in the treatment of B-cell malignancies, underscorin...

詳細記述

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書誌詳細
出版年:Mol Cancer
主要な著者: Ye, Baixin, Stary, Creed M., Li, Xuejun, Gao, Qingping, Kang, Chunsheng, Xiong, Xiaoxing
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815249/
https://ncbi.nlm.nih.gov/pubmed/29448937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0814-0
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