Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation

d‐3‐Phosphoglycerate dehydrogenase (PHGDH) conducts an important step in the synthesis of serine. Importantly, the PHGDH gene is often amplified in certain cancers. Our previous studies revealed that PHGDH gene amplification was associated with poor overall survival in clear cell renal cell carcinom...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Yoshino, Hirofumi, Enokida, Hideki, Osako, Yoichi, Nohata, Nijiro, Yonemori, Masaya, Sugita, Satoshi, Kuroshima, Kazuki, Tsuruda, Masafumi, Tatarano, Shuichi, Nakagawa, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463350/
https://ncbi.nlm.nih.gov/pubmed/32386122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12697
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