Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation

d‐3‐Phosphoglycerate dehydrogenase (PHGDH) conducts an important step in the synthesis of serine. Importantly, the PHGDH gene is often amplified in certain cancers. Our previous studies revealed that PHGDH gene amplification was associated with poor overall survival in clear cell renal cell carcinom...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Yoshino, Hirofumi, Enokida, Hideki, Osako, Yoichi, Nohata, Nijiro, Yonemori, Masaya, Sugita, Satoshi, Kuroshima, Kazuki, Tsuruda, Masafumi, Tatarano, Shuichi, Nakagawa, Masayuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463350/
https://ncbi.nlm.nih.gov/pubmed/32386122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12697
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