Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation

d‐3‐Phosphoglycerate dehydrogenase (PHGDH) conducts an important step in the synthesis of serine. Importantly, the PHGDH gene is often amplified in certain cancers. Our previous studies revealed that PHGDH gene amplification was associated with poor overall survival in clear cell renal cell carcinom...

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Veröffentlicht in:Mol Oncol
Hauptverfasser: Yoshino, Hirofumi, Enokida, Hideki, Osako, Yoichi, Nohata, Nijiro, Yonemori, Masaya, Sugita, Satoshi, Kuroshima, Kazuki, Tsuruda, Masafumi, Tatarano, Shuichi, Nakagawa, Masayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463350/
https://ncbi.nlm.nih.gov/pubmed/32386122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12697
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