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Connexin Mutants Compromise the Lens Circulation and Cause Cataracts through Biomineralization

Gap junction-mediated intercellular communication facilitates the circulation of ions, small molecules, and metabolites in the avascular eye lens. Mutants of the lens fiber cell gap junction proteins, connexin46 (Cx46) and connexin50 (Cx50), cause cataracts in people and in mice. Studies in mouse mo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Berthoud, Viviana M., Gao, Junyuan, Minogue, Peter J., Jara, Oscar, Mathias, Richard T., Beyer, Eric C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461132/
https://ncbi.nlm.nih.gov/pubmed/32823750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165822
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