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Connexin Mutants Compromise the Lens Circulation and Cause Cataracts through Biomineralization

Gap junction-mediated intercellular communication facilitates the circulation of ions, small molecules, and metabolites in the avascular eye lens. Mutants of the lens fiber cell gap junction proteins, connexin46 (Cx46) and connexin50 (Cx50), cause cataracts in people and in mice. Studies in mouse mo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Berthoud, Viviana M., Gao, Junyuan, Minogue, Peter J., Jara, Oscar, Mathias, Richard T., Beyer, Eric C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461132/
https://ncbi.nlm.nih.gov/pubmed/32823750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165822
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