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Connexin Mutants Compromise the Lens Circulation and Cause Cataracts through Biomineralization
Gap junction-mediated intercellular communication facilitates the circulation of ions, small molecules, and metabolites in the avascular eye lens. Mutants of the lens fiber cell gap junction proteins, connexin46 (Cx46) and connexin50 (Cx50), cause cataracts in people and in mice. Studies in mouse mo...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7461132/ https://ncbi.nlm.nih.gov/pubmed/32823750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165822 |
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