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Translation of small downstream ORFs enhances translation of canonical main open reading frames

In addition to canonical open reading frames (ORFs), thousands of translated small ORFs (containing less than 100 codons) have been identified in untranslated mRNA regions (UTRs) across eukaryotes. Small ORFs in 5′ UTRs (upstream (u)ORFs) often repress translation of the canonical ORF within the sam...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Wu, Qiushuang, Wright, Matthew, Gogol, Madelaine M, Bradford, William D, Zhang, Ning, Bazzini, Ariel A
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459409/
https://ncbi.nlm.nih.gov/pubmed/32744758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104763
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