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Translation of small downstream ORFs enhances translation of canonical main open reading frames

In addition to canonical open reading frames (ORFs), thousands of translated small ORFs (containing less than 100 codons) have been identified in untranslated mRNA regions (UTRs) across eukaryotes. Small ORFs in 5′ UTRs (upstream (u)ORFs) often repress translation of the canonical ORF within the sam...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Wu, Qiushuang, Wright, Matthew, Gogol, Madelaine M, Bradford, William D, Zhang, Ning, Bazzini, Ariel A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459409/
https://ncbi.nlm.nih.gov/pubmed/32744758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104763
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