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KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

G protein-coupled receptor kinase 5 (GRK5) has been considered as a potential target for the treatment of heart failure as it has been reported to be an important regulator of pathological cardiac hypertrophy. To discover novel scaffolds that selectively inhibit GRK5, we have identified a novel smal...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Biomol Ther (Seoul)
Κύριοι συγγραφείς: Lee, Jeong Hyun, Seo, Ho Won, Ryu, Jae Yong, Lim, Chae Jo, Yi, Kyu Yang, Oh, Kwang-Seok, Lee, Byung Ho
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Korean Society of Applied Pharmacology 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457178/
https://ncbi.nlm.nih.gov/pubmed/32856617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.129
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