Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension

BACKGROUND: ADRB1 (adrenergic receptor beta 1) responds to neuroendocrine stimulations, which have great implications in hypertension. GRK2 (G protein‐coupled receptor kinase 2) is an essential regulator for many G protein‐coupled receptors and subsequent cell signaling cascades, but its role as a r...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Sun, Xuejing, Zhou, Mengli, Wen, Gaiyan, Huang, Yun, Wu, Junru, Peng, Liping, Jiang, Weihong, Yuan, Hong, Lu, Yao, Cai, Jingjing
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955481/
https://ncbi.nlm.nih.gov/pubmed/33372534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.016364
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