KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

G protein-coupled receptor kinase 5 (GRK5) has been considered as a potential target for the treatment of heart failure as it has been reported to be an important regulator of pathological cardiac hypertrophy. To discover novel scaffolds that selectively inhibit GRK5, we have identified a novel smal...

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Xehetasun bibliografikoak
Argitaratua izan da:Biomol Ther (Seoul)
Egile Nagusiak: Lee, Jeong Hyun, Seo, Ho Won, Ryu, Jae Yong, Lim, Chae Jo, Yi, Kyu Yang, Oh, Kwang-Seok, Lee, Byung Ho
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Korean Society of Applied Pharmacology 2020
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7457178/
https://ncbi.nlm.nih.gov/pubmed/32856617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.129
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