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Mathematical model of colorectal cancer initiation

Quantifying evolutionary dynamics of cancer initiation and progression can provide insights into more effective strategies of early detection and treatment. Here we develop a mathematical model of colorectal cancer initiation through inactivation of two tumor suppressor genes and activation of one o...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Paterson, Chay, Clevers, Hans, Bozic, Ivana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456111/
https://ncbi.nlm.nih.gov/pubmed/32788368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003771117
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