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On measuring selection in cancer from subclonal mutation frequencies

Recently available cancer sequencing data have revealed a complex view of the cancer genome containing a multitude of mutations, including drivers responsible for cancer progression and neutral passengers. Measuring selection in cancer and distinguishing drivers from passengers have important implic...

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Udgivet i:PLoS Comput Biol
Main Authors: Bozic, Ivana, Paterson, Chay, Waclaw, Bartlomiej
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6788714/
https://ncbi.nlm.nih.gov/pubmed/31557163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007368
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