DOCK8 is essential for LFA-1–dependent positioning of T follicular helper cells in germinal centers

T follicular helper (Tfh) cell migration into germinal centers (GCs) is essential for the generation of GC B cells and antibody responses to T cell–dependent (TD) antigens. This process requires interactions between lymphocyte function–associated antigen 1 (LFA-1) on Tfh cells and ICAMs on B cells....

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Janssen, Erin, Tohme, Mira, Butts, Jordan, Giguere, Sophie, Sage, Peter T., Velázquez, Francisco E., Kam, Christy, Milin, Elena, Das, Mrinmoy, Sobh, Ali, Al-Tamemi, Salem, Luscinskas, Francis W., Batista, Facundo, Geha, Raif S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2020
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455063/
https://ncbi.nlm.nih.gov/pubmed/32573493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134508
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