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Mathematical modelling reveals cellular dynamics within tumour spheroids

Tumour spheroids are widely used as an in vitro assay for characterising the dynamics and response to treatment of different cancer cell lines. Their popularity is largely due to the reproducible manner in which spheroids grow: the diffusion of nutrients and oxygen from the surrounding culture mediu...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Bull, Joshua A., Mech, Franziska, Quaiser, Tom, Waters, Sarah L., Byrne, Helen M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455028/
https://ncbi.nlm.nih.gov/pubmed/32810174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007961
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