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Mathematical modelling reveals cellular dynamics within tumour spheroids

Tumour spheroids are widely used as an in vitro assay for characterising the dynamics and response to treatment of different cancer cell lines. Their popularity is largely due to the reproducible manner in which spheroids grow: the diffusion of nutrients and oxygen from the surrounding culture mediu...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Bull, Joshua A., Mech, Franziska, Quaiser, Tom, Waters, Sarah L., Byrne, Helen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455028/
https://ncbi.nlm.nih.gov/pubmed/32810174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007961
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