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Mathematical modelling of telomere length dynamics

Telomeres are repetitive DNA sequences located at the ends of chromosomes. During cell division, an incomplete copy of each chromosome’s DNA is made, causing telomeres to shorten on successive generations. When a threshold length is reached replication ceases and the cell becomes ‘senescent’. In thi...

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Bibliografski detalji
Izdano u:J Math Biol
Glavni autori: Wattis, Jonathan A. D., Qi, Qi, Byrne, Helen M
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028829/
https://ncbi.nlm.nih.gov/pubmed/31728621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00285-019-01448-y
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