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Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs
Telomeres are guanine-rich sequences at the end of chromosomes which shorten during each replication event and trigger cell cycle arrest and/or controlled death (apoptosis) when reaching a threshold length. The enzyme telomerase replenishes the ends of telomeres and thus prolongs the life span of ce...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975128/ https://ncbi.nlm.nih.gov/pubmed/23620229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00285-013-0678-2 |
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