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Mathematical modelling of telomere length dynamics

Telomeres are repetitive DNA sequences located at the ends of chromosomes. During cell division, an incomplete copy of each chromosome’s DNA is made, causing telomeres to shorten on successive generations. When a threshold length is reached replication ceases and the cell becomes ‘senescent’. In thi...

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Bibliografiske detaljer
Udgivet i:J Math Biol
Main Authors: Wattis, Jonathan A. D., Qi, Qi, Byrne, Helen M
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028829/
https://ncbi.nlm.nih.gov/pubmed/31728621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00285-019-01448-y
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