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A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud

Mathematics is often used to model biological systems. In mammary gland development, mathematical modeling has been limited to acinar and branching morphogenesis and breast cancer, without reference to normal duct formation. We present a model of ductal elongation that exploits the geometrically-con...

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Bibliografiska uppgifter
I publikationen:PLoS Comput Biol
Huvudupphovsmän: Paine, Ingrid, Chauviere, Arnaud, Landua, John, Sreekumar, Amulya, Cristini, Vittorio, Rosen, Jeffrey, Lewis, Michael T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845990/
https://ncbi.nlm.nih.gov/pubmed/27115287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004839
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