Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation

Systemic hormones and local growth factor-mediated tissue interactions are essential for mammary gland development. Using phenotypic and transplantation analyses of mice carrying the mesenchymal dysplasia (mes) allele of patched 1 (Ptch1(mes)), we found that Ptch1(mes) homozygosity led to either com...

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Main Authors: Moraes, Ricardo C., Chang, Hong, Harrington, Nikesha, Landua, John D., Prigge, Jonathan T., Lane, Timothy F., Wainwright, Brandon J., Hamel, Paul A., Lewis, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado: Company of Biologists 2009
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675781/
https://ncbi.nlm.nih.gov/pubmed/19297414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.023994
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