A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud

Mathematics is often used to model biological systems. In mammary gland development, mathematical modeling has been limited to acinar and branching morphogenesis and breast cancer, without reference to normal duct formation. We present a model of ductal elongation that exploits the geometrically-con...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Comput Biol
Prif Awduron: Paine, Ingrid, Chauviere, Arnaud, Landua, John, Sreekumar, Amulya, Cristini, Vittorio, Rosen, Jeffrey, Lewis, Michael T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845990/
https://ncbi.nlm.nih.gov/pubmed/27115287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004839
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