טוען...

Cumulative deamidations of the major lens protein γS‐crystallin increase its aggregation during unfolding and oxidation

Age‐related lens cataract is the major cause of blindness worldwide. The mechanisms whereby crystallins, the predominant lens proteins, assemble into large aggregates that scatter light within the lens, and cause cataract, are poorly understood. Due to the lack of protein turnover in the lens, cryst...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Protein Sci
Main Authors: Vetter, Calvin J., Thorn, David C., Wheeler, Samuel G., Mundorff, Charlie C., Halverson, Kate A., Wales, Thomas E., Shinde, Ujwal P., Engen, John R., David, Larry L., Carver, John A., Lampi, Kirsten J.
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley & Sons, Inc. 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7454558/
https://ncbi.nlm.nih.gov/pubmed/32697405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3915
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