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Deamidation alters interactions of β-crystallins in hetero-oligomers

PURPOSE: Cataracts are a major cause of blindness worldwide. A potential mechanism for loss of visual acuity may be due to light scattering from disruption of normal protein–protein interactions. During aging, the lens accumulates extensively deamidated crystallins. We have previously reported that...

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Detalhes bibliográficos
Main Authors: Takata, Takumi, Woodbury, Luke G., Lampi, Kirsten J.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633459/
https://ncbi.nlm.nih.gov/pubmed/19190732
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