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Solvent accessibility of βB2-crystallin and local structural changes due to deamidation at the dimer interface

In the lens of the eye the ordered arrangement of the major proteins, the crystallins, contributes to lens transparency. Members of the β/γ-crystallin family share common β-sheet rich domains and hydrophobic regions at the monomer-monomer or domain-domain interfaces. Disruption of these interfaces,...

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Detalhes bibliográficos
Main Authors: Takata, Takumi, Smith, Joshua P., Arbogast, Brian, David, Larry L., Lampi, Kirsten J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926248/
https://ncbi.nlm.nih.gov/pubmed/20639133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2010.05.019
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